Orchid Biosciences, Inc.

DateInflation Amount Per Share*
5/5/2000**$0.07699***
5/8/2000$0.77176
5/9/2000$1.0275
5/10/2000$0.88194
5/11/2000$0.44569
5/12/2000$0.33931
5/15/2000$0.28984
5/16/2000$0.38821
5/17/2000$0.38118
5/18/2000$0.8425
5/19/2000$1.00454
5/22/2000$1.00309
5/23/2000$1.00848
5/24/2000$0.18903
5/25/2000$0.13718
5/26/2000$0.10047
5/30/2000$0.22617
5/31/2000$0.2564
6/1/2000$0.27737
6/2/2000$0.25056
6/5/2000$1.0275
6/6/2000$1.0275
6/7/2000$1.0275
6/8/2000$1.0275
6/9/2000$1.0275
6/12/2000$1.0275
6/13/2000$1.0275
6/14/2000$1.0275
6/15/2000$1.0275
6/16/2000$1.0275
6/19/2000$1.0275
6/20/2000$1.0275
6/21/2000$1.0275
6/22/2000$1.0275
6/23/2000$1.0275
6/26/2000$1.0275
6/27/2000$1.0275
6/28/2000$1.0275
6/29/2000$1.0275
6/30/2000$1.0275
7/3/2000$1.0275
7/5/2000$1.0275
7/6/2000$1.0275
7/7/2000$1.0275
7/10/2000$1.0275
7/11/2000$1.0275
7/12/2000$1.0275
7/13/2000$1.0275
7/14/2000$1.0275
7/17/2000$1.0275
7/18/2000$1.0275
7/19/2000$1.0275
7/20/2000$1.0275
7/21/2000$1.0275
7/24/2000$1.0275
7/25/2000$1.0275
7/26/2000$1.0275
7/27/2000$1.0275
7/28/2000$1.0275
7/31/2000$1.0275
8/1/2000$1.0275
8/2/2000$1.0275
8/3/2000$1.0275
8/4/2000$1.0275
8/7/2000$1.0275
8/8/2000$1.0275
8/9/2000$1.0275
8/10/2000$1.0275
8/11/2000$1.0275
8/14/2000$1.0275
8/15/2000$1.0275
8/16/2000$1.0275
8/17/2000$1.0275
8/18/2000$1.0275
8/21/2000$1.0275
8/22/2000$1.0275
8/23/2000$1.0275
8/24/2000$1.0275
8/25/2000$1.0275
8/28/2000$1.0275
8/29/2000$1.0275
8/30/2000$1.0275
8/31/2000$1.0275
9/1/2000$1.0275
9/5/2000$1.0275
9/6/2000$1.0275
9/7/2000$1.0275
9/8/2000$1.0275
9/11/2000$1.0275
9/12/2000$1.0275
9/13/2000$1.0275
9/14/2000$1.0275
9/15/2000$1.0275
9/18/2000$1.0275
9/19/2000$1.0275
9/20/2000$1.0275
9/21/2000$1.0275
9/22/2000$1.0275
9/25/2000$1.0275
9/26/2000$1.0275
9/27/2000$1.0275
9/28/2000$1.0275
9/29/2000$1.0275
10/2/2000$1.0275
10/3/2000$1.0275
10/4/2000$1.0275
10/5/2000$1.0275
10/6/2000$1.0275
10/9/2000$1.0275
10/10/2000$1.0275
10/11/2000$1.0275
10/12/2000$1.0275
10/13/2000$1.0275
10/16/2000$1.0275
10/17/2000$1.0275
10/18/2000$1.0275
10/19/2000$1.0275
10/20/2000$1.0275
10/23/2000$1.0275
10/24/2000$1.0275
10/25/2000$1.0275
10/26/2000$1.0275
10/27/2000$1.0275
10/30/2000$1.0275
10/31/2000$1.0275
11/1/2000$1.0275
11/2/2000$1.0275
11/3/2000$1.0275
11/6/2000$1.0275
11/7/2000$1.0275
11/8/2000$1.0275
11/9/2000$1.0275
11/10/2000$1.0275
11/13/2000$1.0275
11/14/2000$1.0275
11/15/2000$1.0275
11/16/2000$1.0275
11/17/2000$1.0275
11/20/2000$1.0275
11/21/2000$1.0275
11/22/2000$1.0275
11/24/2000$1.0275
11/27/2000$1.0275
11/28/2000$0.28029
11/29/2000$0.54311
11/30/2000$0.4812
12/1/2000$0.57046
12/4/2000$0.25982
12/5/2000$0
12/6/2000$0

* Data shown are adjusted forward for all stock splits between the IPO and 12/6/00.

** Purchases on a date not listed in the chart above have no artificial inflation.

*** Purchases in the IPO itself at $8.00 per share have no artificial inflation.